Fran Drescher's Virtual Cabaret Spectacular will stream live at 3 PM ET on CancerSchmancer.org.
Olivier winner Lesli Margherita, Steven Weber, Judy Gold, and Ann Hampton Callaway are also on the lineup. Drescher's The Nanny co-star Renée Taylor, who played Fran Fine's mother Sylvia, will partake in the festivities, too.
Cancer Schmancer was founded by Drescher after publishing her book of the same name, chronicling her own battle with cancer. The organization aims to transform the nation’s current health care system using a three-pronged approach of prevention, early detection, and policy change.
Drescher is a Broadway alum, playing Madame in the 2013 revival of Rodgers and Hammerstein's Cinderella. More recently, it was announced that the star was working on a stage version of The Nanny for the Great White Way with a script by Drescher and a score by Emmy-winning Crazy Ex-Girlfriend songwriters Rachel Bloom and the late Adam Schlesinger.