David Lansbury had previously been advertised for the show, though he was never officially announced for the cast. Spiner now has his role. Previews begin March 11.
"Star Trek" vet Spiner starred on Broadway in the Roundabout Theatre Company's praised production of 1776 several seasons back. His other theatre credits include Big River and Sunday in the Park with George.
Emond last acted in Homebody/Kabul and Lansbury is currently in Comedians.
French playwright Reza had a big hit with her first Broadway play, Art, which won a Tony Award for Best Play. Her second New York premiere, The Unexpected Man played Off-Broadway in 2000.
Matthew Warchus, who piloted Art, will stage Life. Since Art, Warchus has scored a hit with True West and a miss with the Broadway revival of Follies. Ron Kastner is producing.
In Life, a couple are putting their son to bed when their dinner guests arrive — 24 hours early! The unexpected evening then splits into three possible outcomes — hence the play's title.
Reza has never lacked for star talent in her works. Art debuted in New York with Victor Garber, Alan Alda and Alfred Molina and proceeded to host a series of boldface casts, as did the original London production. Unexpected Man, meanwhile, starred Eileen Atkins and Alan Bates.
Tickets for Life are now on sale at Telecharge, (212) 239-6200.