As this is the new play by Lindsay-Abaire, who wrote the quirky comedies Fuddy Meers, Kimberly Akimbo and Wonder of the World, expect humor to lace the tragedy.

The play is billed as "a bittersweet drama about finding hope in the lowest moments of our lives, and the paths we take to return to the light of day."

Daniel Sullivan (Proof, Sight Unseen, Brooklyn Boy, Julius Caesar) directs a company that also includes Tyne Daly (as Becca's mom, Nat), John Gallagher Jr. (as neighborhood teen Jason) and Mary Catherine Garrison (as Becca's sister, Izzy).

According to MTC, "Becca (Nixon) and Howie Corbett (Slattery) have everything they could want, until a life-shattering accident turns their world upside down, and leaves the couple drifting perilously apart. Becca, who must also cope with the distractions of her reckless sister Izzy (Garrison), and their opinionated mother, Nat (Daly), takes solace in her unlikely friendship with a neighborhood teenager, Jason (Gallagher), who might provide the key to lead her back from the darkest of places."

Rabbit Hole marks the Broadway debut of Lindsay-Abaire, a favorite writer of MTC, which presented his Fuddy Meers, Wonder of the World and Kimberly Akimbo Off-Broadway. Lindsay-Abaire is also currently working the Broadway-aimed musicals High Fidelity and Shrek. He is currently writing the screen adaptation of the novel "Inkheart" by Cornelia Funke for Newline Features, as well as a screen adaptation of Kimberly Akimbo for Dreamworks. Daly last appeared on Broadway in 1992 in a revival of Chekov's The Seagull opposite Jon Voight, Laura Linney, and Ethan Hawke. She received the 1990 Tony Award for Best Actress in a Musical for her portrayal of Rose in Gypsy directed by Arthur Laurents. For her work in television, she won six Emmy Awards (four for "Cagney and Lacey," one for "Christy" and one "Judging Amy."

Gallagher previously appeared in David Lindsay-Abaire's Kimberly Akimbo both at MTC and at South Coast Repertory Theatre. He was nominated for a Los Angeles Drama Critics Circle Award for his performance in the show. He made his Off-Broadway debut at the age of 15 in Current Events, at MTC.

Garrison most recently appeared on Broadway in the Roundabout revival of Assassins (as Lynette "Squeaky" Fromme).

Nixon appeared on Broadway in The Women, The Last Night of Ballyhoo, Indiscretions (Tony nomination), Angels in America, The Heidi Chronicles, Hurlyburly and The Real Thing (simultaneously) and The Philadelphia Story. She is internationally known as Mirana on TV's "Sex and the City."

Slattery appeared on Broadway in Betrayal and Laughter on the 23rd Floor, and has appeared in five other MTC productions, including the original production of Richard Greenberg's Three Days of Rain in 1997. His recent television credits include the critically acclaimed series, "Jack and Bobby."

The creative team for Rabbit Hole includes John Lee Beatty (set design), Jennifer von Mayrhauser (costume design), Christopher Akerlind (lighting design), and John Gromada (sound design and original music).

Rabbit Hole will open Feb. at the Biltmore Theatre, 261 W. 47th Street.

For tickets or information, visit TeleCharge.com or call (212) 239-6200 or visit www.manhattantheatreclub.com.