The Off-Broadway premiere of Hir, a "subversive" comedy by Obie Award winner Mac and helmed by Niegel Smith, is led by Tony nominee and two-time Obie winner Nielsen (Vanya and Sonia and Masha and Spike). Nielsen plays a wife and mother who finds herself liberated from an oppressive marriage and "on a crusade to dismantle the patriarchy," state press notes. Phelan is set to play her son, who is "newly out transgender," and his mother's ally. 

The cast will also feature Daniel Oreskes (Billy Elliott) and Cameron Scoggins (Pocatello). Performances will run Oct. 16-Nov. 29, with an official opening night scheduled for Nov. 8.

Playwrights Horizons has also announced that the cast of Marjorie Prime will be led by "True Blood" actress Smith, last seen on Broadway in Buried Child and The Grapes of Wrath. Smith is joined by Noah Bean (The Rise and Fall of Annie Hall), Lisa Emery (Casa Valentina) and Stephen Root (All My Sons).

Harrison's futuristic play explores the mysteries of human identity and the limitless potential of technology, as 86-year old Marjorie, played by Smith, is retold the story of her life by an artificially intelligent being.

Performances are set to begin Nov. 20, with an official opening night on Dec. 14. The limited engagement will play through Jan. 3, 2016.

Tickets for both productions will go on sale to the general public in the fall. For more information on the season, visit PlaywrightsHorizons.