Spader, who plays CEO Robert California of Sabre, joined the cast after Emmy winner Steve Carell, who played Michael Scott, departed the series.
"James always wanted this to be a one-year arc, and he now leaves us having created one of the most enigmatic and dynamic characters in television," executive producer Paul Lieberstein said in a statement. "He’s been a great friend to me and the show, helping us successfully transition into the post-Michael Scott years, and I’m grateful for that. I’m already looking for ways to work with him again."
"The Office" is executive-produced by Ben Silverman, Greg Daniels, Ricky Gervais, Stephen Merchant, Howard Klein and Lieberstein.
The series airs Thursday nights at 9 PM ET on NBC.