The musical is currently nominated for 11 Olivier Awards, London's top theatrical honors.
The stage and screen star will reprise his Tony-winning role of Aaron Burr in the Lin-Manuel Miranda musical.
Nick Mohammed will host the April 12 ceremony for the London theatrical honors.
Based on the Roald Dahl novel, Matilda features a score by Tim Minchin and a Tony Award-winning book by Dennis Kelly.
Director Federico Bellone's take on the 1987 film will play the purpose-built Capital Theatre.
Sadie Sink and Noah Jupe are leading Robert Icke's new staging of the Shakespearean tragedy.
Jamaal Fields-Green heads the cast at the Prince Edward.
Lindsay Posner will direct Christopher Hampton's translation of Florian Zeller's comedy.
What's announced and what's in previews in the West End.