"Partners," which features an all-male lineup of guest stars, including Streisand's son, Jason Gould, arrives in stores Sept. 16.
Click through to watch some of our favorite performances from Streisand's partners over the years.
Perhaps her most iconic duet, performing "Get Happy/Happy Days Are Here Again" with Judy Garland.
The making of "Tell Him" with Celine Dion.
"Close to You" with Burt Bacharach.
"Guilty" with Barry Gibb.
Barbra and Judy's "Hooray for Love" medley.
"You Don't Bring Me Flowers" with Neil Diamond.
"Crying Time" and more with Ray Charles.
"What Kind of Fool?" with Barry Gibb.
"Evergreen" with Kris Kristofferson from "A Star Is Born."
Recording "New York State of Mind" with Billy Joel for "Partners."
Recording "How Deep Is the Ocean" with Jason Gould.
Barbra duets with herself for a show-stopping "Yentl" medley.
Her recent comedic medley on "The Tonight Show starring Jimmy Fallon."