According to TVguide.com, the episode will air March 31 and will allow most of the medical drama's cast members (including Caroline, or Change and Avenue Q star Chandra Wilson) to sing, but Ramirez will get the majority of the vocal honors. Many songs featured on the series in the past will be performed in the episode.
"Grey's Anatomy" airs Thursdays at 9 PM ET on ABC. To get a peek at Ramirez' performance, look below: