Performances of the two-hander will officially open Feb. 26.
The musical, which features music by Andrew Lippa, lyrics by Tom Greenwald and a book by Greenwald and Lippa, premiered Off-Broadway in 1995. This production includes the premiere of a new song, "Trouble with Men."
Here's how the production is billed: "John & Jen is an intimate story about connections, commitments and the healing of the human heart."
"I am thrilled to be working with the wonderful Kate Baldwin on John & Jen, Keen Company's second musical," Jonathan Silverstein, Keen artistic director, said in a previous statement. "Not only is Kate well versed in Andrew Lippa's music, but her emotional range and intelligence is a perfect fit for the complicated role of Jen. Andrew and Tom have been busy fine tuning the piece and I eagerly look forward to presenting this touching story in our intimate home at The Clurman on Theatre Row."
Baldwin received a Tony nomination for her performance in Finian's Rainbow. Her Broadway credits also include Big Fish, The Full Monty, Thoroughly Modern Millie and Wonderful Town. Her stage work also includes Giant, Can-Can and South Pacific.
Along with Cinderella, Ryan has performed in The Public Theater production of The Fortress of Solitude.
The Clurman Theatre at Theatre Row is located at 410 West 42nd Street, between 9th and 10th Aves. For more information, visit keencompany.org.