Gisela Cardenas (Agamemnon) will direct the musical, which is slated to begin Sept. 10 at the refurbished Sanford Meisner Theater for a run through Oct. 6.

John Kander, Fred Ebb and Terrence McNally's musical take on Manuel Puig's "dark tale of torture and imprisonment" will undergo a new staging that, according to an announcement, will "join political ideology with a cabaret aesthetic."

Milica Paranosic will provide musical direction. The design team features Jian Jung (set), Lucrecia Briceno (lighting) and Oana Botez-Ban (costumes). Cara Scarmack serves as assistant director.

The Vortex has been in residence at the Sanford Meisner Theater since 1983. The company, which "is dedicated to creating and producing a diverse range of classical texts reconstructed for a contemporary audience," earned a 2007 Drama Desk nomination for its revival of H.M.S. Pinafore. Previous productions include Agamemnon, In Delirium: after the sorrows of young werther, Deviant and Bathsheba Doran's adaptation of Maurice Maeterlink's the blind.

Tickets for Kiss of the Spider Woman at the Sanford Meisner Theater, 164 Eleventh Ave. (between 22nd and 23rd St.), are available by calling (212) 352-3101.