Emmy winner and Cheers star Rhea Perlman is replacing Rosie O’Donnell as Nora in The New Group's production of Good for Otto by David Rabe. O’Donnell, according to a press representative, is no longer able to perform in the Off-Broadway production due to illness.

Perlman is a four-time Emmy winner for her performance on the NBC show Cheers, a role which saw her nominated 10 times during the 11-year series. Onstage, she has been seen on Broadway in The Tale of the Allergist’s Wife, and Off-Broadway in The Exonerated and Love, Loss and What I Wore, among others.

She joins the previously announced F. Murray Abraham, Kate Buddeke, Laura Esterman, Nancy Giles, Lily Gladstone, Ed Harris, Charlotte Hope, Mark Linn-Baker, Amy Madigan, Rileigh McDonald, Kenny Mellman, Maulik Pancholy, and Michael Rabe in the New York premiere. Scott Elliott directs.

Performances of Good for Otto will still begin as planned February 20 in the Alice Griffin Jewel Box Theatre in the Pershing Square Signature Center. Opening night is set for March 8.

Rabe's play, which premiered at Chicago's Gift Theatre in 2015, explores the relationships between health professionals, patients, and families in a rural Connecticut mental health center.

The production will feature scenic design by Derek McLane, costume design by Jeff Mahshie, lighting design by Jeff Croiter, and sound design by Rob Milburn and Michael Bodeen. Casting by Judy Henderson, CSA. Production stage manager is Valerie A. Peterson.

Performances are currently scheduled through April 1.